A hybrid version of MVTools+CUDA doesn't sound very promising to me. If you look at e.g. MDegrain2, you'll find the whole thing spends like 65% of its time on SuperClip+VectorSearch, 25% on the (block overlapped) compensation while the denoiser fetches pixels, and only 10% time on the actual denoisi...

OH COOL!!! I hope your first one will be a denoiser. Avisynth script denoisers can be painfully slow (like mc_spuds, MCTemporalDenoise, etc...). Those are highly sophisticated denoising scripts, making very big effort to come to an optimal result. An important part of the big effort is active motio...